What happens once you realise you have suffered severe childhood trauma? Cecilia reveals a bilateral approach to being bipolar…
COVID CONFABS – E06
How does childhood trauma launch us towards psychiatric issues later in life? Laurence alludes to her own experience and fingers “hypersensitivity” as the culprit…
Meeting 3 Episode 6 – How useful is a diagnosis?
Is diagnosis and subsequent labelling a help or hindrance to people living with mental illness? Kristina touches on the potential for rejection sensitive dysphoria (RSD) in people with severe depression while Alexandre adds n since to the debate…
Meeting 1 Episode 7 – Can you actually tell when someone is better?
EEG readings indicate that significant changes are taking place in brain activity even before clinical observations show improvement. But there are problems inherent to the experimental process and Micah hopes SYNERGIES can go some way to providing a solution…
Meeting 03 Episode 01 – What do we mean by “trauma”? – A second look…
What do we mean when we talk about “trauma”? Isabelle and her PLEX-RPs take another shot at defining the phenomenon at the heart of her research – without which, a deeper understanding of the scientific and clinical ramifications are difficult to determine…
COVID CONFABS – E05
When things go wrong in childhood, it isn’t just the child who suffers. Isabelle offers some hope and scientific evidence of how this deeply disturbing reality might be avoided…
Meeting 3 Episode 5 – Is there a lag between lab and clinic?
“Bench to Bed” is a phrase frequently used to describe an idealised relationship between research and clinical practice – Kristine explains to the PLEX-RPs one reason why this process isn’t quite as simple as it sounds…
Meeting 02 Episode 07 – Why use mice for these experiments?
Epigenetics or just plain old genetic variability? Tracking changes in DNA means you need to start with a level playing field and Isabelle explains why mice are the model subject…
Meeting 1 Episode 6 – Does the Analysis Include the Individual’s Past and Present Context?
Is “personalised medicine” excluded when building clinical models using large data sets – Micah brings some balance to the paradox…
COVID CONFABS – E04
Isabelle introduces the “Early Cause” consortium while experiments carried out during lockdown find a link between cardiovascular disease and trans-generational trauma…