PERTH – GLAD


GLAD (Genetics
Linked to Anti
-Depressants)

Using pharmacogenomics (PG) (the study of how a person’s genetic make-up influences how they metabolise medication), the trial will analyse whether PG-guided treatment is more effective than today’s widely adopted ‘trial and error’ approach.

PERTH - GLAD

Latest Episode

  • Synergies- Perth GLAD

    Meeting 03 Episode 05 – Riding the Resistance Roller Coaster…

    In this longer than usual episode, Sean gives an in-depth explanation of what constitutes 'resistance' and how the GLAD projects addresses this problem... +

  • Synergies – Perth GLAD

    Meeting 01 Episode 01 – GLAD to be a world first…

    In this opening episode, after a spin through the funding landscape, PI Sean reveals the groundbreaking impetus behind the GLAD project - PLEX POWERED RESEARCH… +

  • Synergies – Perth GLAD

    Meeting 01 Episode 02 – “Repurposing the past…”

    Genetic “profiling" to optimise medication choice (Pharmacogenomics) has historically been priced out of the mainstream. Sean explains why this SYNERGIES programme could radically alter that situation... +

  • Synergies – Perth GLAD

    Meeting 01 Episode 03 – “Pimp my Dose…”

    In a world where everyone starts off as "the norm”, when it comes to prescribing drugs, and then experiences the inevitable "suck it and see” effect, pharmacogenetics can identify more readily and accurately which direction to go in when looking +

  • Synergies – Perth GLAD

    Meeting 01 Episode 04 – “Keep taking the meds…”

    Asked if psychogenetic profiling could alleviate the “rollercoaster” effect frequently associated with current medication regimes, Sean points out one of the universal truths hindering treatment using prescribed drugs - you gotta go the distance... +

Research Partners

PastedGraphic-1 - copie

Sue – PLEX RP

PERTH - Sean

Sean – Research PI

  • Synergies – Perth GLAD

    Meeting 02 Episode 01 – “A real-world example”

    Sean takes time to recount the story of Cindy Black, an early enrolee in multi-gene testing for molecular matching. After many years of living with debilitating depression, Cindy went for broke, took the test and changed her life... +

  • Synergies – Perth GLAD

    Meeting 02 Episode 02 – Does dose matter more…?

    Does the test help to establish the optimal dosage of an existing drug regime or is it designed to indicate which molecule to use in the first place? Sean explains the way the body processes drugs to clarify the situation... +

  • Synergies – Perth GLAD

    Meeting 02 Episode 03 – “Putting order into disorders…”

    Does the test help to establish the optimal dosage of an existing drug regime or is it designed to indicate which molecule to use in the first place? Sean explains the way the body processes drugs to clarify the situation... +

Research Partners

PastedGraphic-1 - copie

Sue – PLEX RP

PERTH - Sean

Sean – Research PI

  • Synergies- Perth GLAD

    Meeting 03 Episode 01 – So who are we going to play upfront?

    Now the preliminary discussions are over, Sean and the GLAD PLEX-RPs begin to address the prerequisites for the research project - first up is filling the PhD candidate for the PI position... +

  • Synergies- Perth GLAD

    Meeting 03 Episode 02 – “Dotting the ethical t’s and I’s…”

    Sean raises the all-important question of adhering to the ethics board's stipulations and suggests that PLEX involvement could be considered an extra level of compliance… +

  • Synergies- Perth GLAD

    Meeting 03 Episode 03 – Keeping our credentials in the clear…

    The GLAD team evoke the power of disclosure when collaborating with PLEX RPs. +

  • Synergies- Perth GLAD

    Meeting 03 Episode 04 – A minefield made of meds…

    The GLAD team evoke the power of disclosure when collaborating with PLEX RPs. +

  • Synergies- Perth GLAD

    Meeting 03 Episode 05 – Riding the Resistance Roller Coaster…

    In this longer than usual episode, Sean gives an in-depth explanation of what constitutes 'resistance' and how the GLAD projects addresses this problem... +

Research Partners

PastedGraphic-1 - copie

Sue – PLEX RP

PERTH - Sean

Sean – Research PI

  • Synergies – Perth GLAD

    Meeting 04 Episode 01 – Whose ‘Psy-ed’ are you on?

    The GLAD group get our PI Sean to elaborate on the academic and practical niceties of Psychologist versus Psychiatrist... +

Research Partners

PastedGraphic-1 - copie

Sue – PLEX RP

PERTH - Sean

Sean – Research PI

MORE PROJECTS

Laboratory of Neuro-epigenetics, University and ETH
Laboratory for Investigative Neurophysiology, CHUV
University Hospital of Psychiatry and Psychotherapy
Perron Institute and UWA Medical School
PERTH - rTMS