GLAD (Genetics
Using pharmacogenomics (PG) (the study of how a person’s genetic make-up influences how they metabolise medication), the trial will analyse whether PG-guided treatment is more effective than today’s widely adopted ‘trial and error’ approach.
PERTH - GLAD
Latest Episode
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Meeting 03 Episode 05 – Riding the Resistance Roller Coaster…
In this longer than usual episode, Sean gives an in-depth explanation of what constitutes 'resistance' and how the GLAD projects addresses this problem... +
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Meeting 01 Episode 01 – GLAD to be a world first…
In this opening episode, after a spin through the funding landscape, PI Sean reveals the groundbreaking impetus behind the GLAD project - PLEX POWERED RESEARCH… +
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Meeting 01 Episode 02 – “Repurposing the past…”
Genetic “profiling" to optimise medication choice (Pharmacogenomics) has historically been priced out of the mainstream. Sean explains why this SYNERGIES programme could radically alter that situation... +
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Meeting 01 Episode 03 – “Pimp my Dose…”
In a world where everyone starts off as "the norm”, when it comes to prescribing drugs, and then experiences the inevitable "suck it and see” effect, pharmacogenetics can identify more readily and accurately which direction to go in when looking +
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Meeting 01 Episode 04 – “Keep taking the meds…”
Asked if psychogenetic profiling could alleviate the “rollercoaster” effect frequently associated with current medication regimes, Sean points out one of the universal truths hindering treatment using prescribed drugs - you gotta go the distance... +
Research Partners
Sue – PLEX RP
Sean – Research PI
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Meeting 02 Episode 01 – “A real-world example”
Sean takes time to recount the story of Cindy Black, an early enrolee in multi-gene testing for molecular matching. After many years of living with debilitating depression, Cindy went for broke, took the test and changed her life... +
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Meeting 02 Episode 02 – Does dose matter more…?
Does the test help to establish the optimal dosage of an existing drug regime or is it designed to indicate which molecule to use in the first place? Sean explains the way the body processes drugs to clarify the situation... +
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Meeting 02 Episode 03 – “Putting order into disorders…”
Does the test help to establish the optimal dosage of an existing drug regime or is it designed to indicate which molecule to use in the first place? Sean explains the way the body processes drugs to clarify the situation... +
Research Partners
Sue – PLEX RP
Sean – Research PI
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Meeting 03 Episode 01 – So who are we going to play upfront?
Now the preliminary discussions are over, Sean and the GLAD PLEX-RPs begin to address the prerequisites for the research project - first up is filling the PhD candidate for the PI position... +
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Meeting 03 Episode 02 – “Dotting the ethical t’s and I’s…”
Sean raises the all-important question of adhering to the ethics board's stipulations and suggests that PLEX involvement could be considered an extra level of compliance… +
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Meeting 03 Episode 03 – Keeping our credentials in the clear…
The GLAD team evoke the power of disclosure when collaborating with PLEX RPs. +
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Meeting 03 Episode 04 – A minefield made of meds…
The GLAD team evoke the power of disclosure when collaborating with PLEX RPs. +
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Meeting 03 Episode 05 – Riding the Resistance Roller Coaster…
In this longer than usual episode, Sean gives an in-depth explanation of what constitutes 'resistance' and how the GLAD projects addresses this problem... +
Research Partners
Sue – PLEX RP
Sean – Research PI
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Meeting 04 Episode 01 – Whose ‘Psy-ed’ are you on?
The GLAD group get our PI Sean to elaborate on the academic and practical niceties of Psychologist versus Psychiatrist... +
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Meeting 04 Episode 02 – Do all roads lead to psychiatry?
Sean draws a highly informative and amusing sketch of his route to psychiatry and illustrates it with a broad spectrum analysis of the candidates that can constitute this particular branch of the medical sciences… +
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Meeting 04 Episode 03 – Time is of the essence – why are consolations so cursory?
Getting enough time with your psychiatric professional is a recurring preoccupation for anyone dealing with mental health issues. Sean does his best to explain the whys and wherefores of a system under serious duress... +
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Meeting 04 Episode 04 – Working out the paperwork…
Before Sean and his research team can submit a proposal for the study to the ethics board, he opens up the paperwork to the PLEX-RPs, with a view to having their input on a questionnaire aimed at informing and recruiting +
Research Partners
Sue – PLEX RP
Sean – Research PI
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