Isabelle Mansuy and her PLEX Research Partners discuss a number of topics from grant applications to epi-genetics and trauma, visting some old cliches on the way…
ZURICH - Laboratory of Neuro-epigenetics, University and ETH Zurich
Latest Episode
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Meeting 02 Episode 07 – Why use mice for these experiments?
Epigenetics or just plain old genetic variability? Tracking changes in DNA means you need to start with a level playing field and Isabelle explains why mice are the model subject... +
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Meeting 1 Episode 1 – From Purgatory to Paradise
Cutting edge research needs money - Isabelle and her PLEX Research Partners discuss the often fruitless task of finding the funds… +
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Meeting 1 Episode 2 – There Really is a Biological Basis…
On the track of trauma - and Renaud begins to feel the impact of SYNERGIES… +
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Meeting 1 Episode 3 – De-mystification
Isabelle dispels rumours of a “double life” which leads to an exchange around a haunting professional dilemma… +
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Meeting 1 Episode 4 – Useful and Constructive
Isabelle reveals the advantages participating in SYNERGIES and Cecilia evokes the problems she has with taking her medication… +
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Meeting 1 Episode 5 – Some Epigenetic Markers
The meeting begins to get “technical” as Isabelle and Renaud discuss the markers and mechanisms involved in Transgenerational Epigenetic Inheritance (TEI)… +
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Meeting 1 Episode 6 – Another Epigenetic Mechanism
The ZURICH team continue their discussion around DNA and microRNA methylation and touch on the reasons why it is so difficult to treat psychiatric disorders… +
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Meeting 1 Episode 7 – The Limbic System
Renaud outlines his theory of the origins of empathy - much to the amusement of the others in the room… +
Research Partners
Hasna – PLEX RP
Cecilia – PLEX RP
Renaud – PLEX RP
Isabelle – PI
In this second series of videos, Isabelle Mansuy and her PLEX Research Partners, Cecilia, Hasna and Renaud try to draw a circle around the roots and definitions of trauma…
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Meeting 2 Episode 1 – What is trauma?
Isabelle digs deep in an effort to explain what trauma means to her, with a little help from her PLEX Research Partners of course… +
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Meeting 2 Episode 2 – Humiliation – I never thought it could be so destructive…
What shape can trauma take? Isabelle Mansuy’s group touch upon the impact of childhood humiliation... +
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Meeting 2 Episode 3 – The impact of SYNERGIES
Isabelle Mansuy begins a discussion around how SYNERGIES has altered her world view and what this implies for the future of her research... +
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Meeting 2 Episode 4 – Why me?
Cecile attempts to address the injustice of mental illness when she asks "why me?" +
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Meeting 2 Episode 5 – Does This Make You Angry?
Cecilia and Renaud reveal how they deal with anger and how acceptance rather than forgiveness is the more likely the solution... +
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Meeting 2 Episode 6 – The Physical Legacy of Trauma
Trauma - never mind the mind, trauma leaves scars everywhere in the body... +
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Meeting 02 Episode 07 – Why use mice for these experiments?
Epigenetics or just plain old genetic variability? Tracking changes in DNA means you need to start with a level playing field and Isabelle explains why mice are the model subject... +
Research Partners
Hasna – PLEX RP
Cecilia – PLEX RP
Renaud – PLEX RP
Isabelle – PI
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Meeting 03 Episode 01 – What do we mean by “trauma”? – A second look…
What do we mean when we talk about “trauma”? Isabelle and her PLEX-RPs take another shot at defining the phenomenon at the heart of her research - without which, a deeper understanding of the scientific and clinical ramifications are difficult +
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Meeting 03 Episode 02 – How do we deal with the mental fallout of trauma?
What happens once you realise you have suffered severe childhood trauma? Cecilia reveals a bilateral approach to being bipolar... +
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Meeting 03 Episode 03 – The need to network – collaboration between professionals
Psychiatrists vs Psychologists - Cecilia and Hasna discuss the importance of having these two professions work in close collaboration when seeking a balanced approach to treating PLEX +
Research Partners
Hasna – PLEX RP
Cecilia – PLEX RP
Renaud – PLEX RP
Isabelle – PI
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COVID CONFABS – E01
Isabelle Mansuy shares her own "lockdown routine" during the first month of the COVID-19 pandemic... +
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COVID CONFABS – E02
Jacqueline looks back 10 years and compares the current pandemic with her mental state then +
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COVID CONFABS – E03
Isabelle explains how being in lockdown led her team to a new scientific discovery... +
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COVID CONFABS – E04
Isabelle introduces the “Early Cause” consortium while experiments carried out during lockdown find a link between cardiovascular disease and trans-generational trauma... +
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COVID CONFABS – E05
When things go wrong in childhood, it isn’t just the child who suffers. Isabelle offers some hope and scientific evidence of how this deeply disturbing reality might be avoided... +
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COVID CONFABS – E06
How does childhood trauma launch us towards psychiatric issues later in life? Laurence alludes to her own experience and fingers “hypersensitivity” as the culprit... +
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